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Gout1
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Gout

INTRODUCTION Gout (monosodium urate [MSU] crystal deposition disease) is characterized biochemically by extracellular fluid urate saturation, which is reflected in the blood by hyperuricemia, with serum or plasma urate concentrations exceeding 6.8 mg/dL (approximately 400 micromol/L); this level of urate is the approximate limit of urate solubile The clinical manifestations of gout may include: ●Recurrent […]
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Gout
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Gout

TREATMENT OF COMORBIDITIES Weight reduction towards ideal body weight and moderation in ethanol consumption have each been convincingly shown to reduce both the risk of incident gout and the expression of established gout. Other comorbidities have also been the subject of study. Hyperuricemia and gout are frequently accompanied by one or more major disorders, such as […]
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Gout – causes, symptoms, diagnosis, treatment, pathology
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Gout – causes, symptoms, diagnosis, treatment, pathology

LABORATORY FINDINGS Synovial fluid analysis  The gout flare is characterized by the presence of monosodium urate (MSU) crystals in synovial fluid obtained from joints or bursas visualized by direct examination of a sample of fluid using compensated polarized light microscop. Urate crystals may also be identified frequently by this technique in material aspirated during the […]
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Understanding Reactive Arthritis
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Understanding Reactive Arthritis

●Treatment   •Initial therapy We suggest treatment of arthritis in most patients initially with nonsteroidal antiinflammatory drugs (NSAIDs) in antiinflammatory doses (eg, naproxen 500 mg two to three times daily, diclofenac 50 mg three times daily, or indomethacin 50 mg three times daily), rather than starting a disease-modifying antirheumatic drugs (DMARD) upon diagnosis.   •Inadequate response to initial NSAID therapy […]
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